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Vista Biologicals is capable of providing a host of full-spectrum process development services custom-tailored to the specific needs of the client.

Services :: Process Development
Vista Biologicals can assist with the following process development tasks:

Cell Culture

  • Creation of the cell line, either through transformation or transfection with a client-provided vector or by hybridoma fusion.
  • Selection of high productivity clones.
  • Adaptation to serum-free medium, suspension culture, or both.
  • Medium optimization.
Production
  • Process design (batch, fed-batch, perfusion)
  • Optimization of fermentation paramteters (feed rate, temperature, pH, DO, etc.)
Purification
  • Process design and optimization for yield, purity, endotoxin, viral clearance and cost.
  • Assay development